Romaco China Solids Process Center is a single doorstep to provide you the professional assistance for all your questions relating to High-shear granulation, Fluid-bed Granulating - Drying - Coating - Hot melt coating, Tableting and Tablet Coating process for Pharmaceutical, nutraceutical & non-pharma industry. We understand the solids process very well! Are you interested to know more about it?
Poor flowability of product
Variation in content uniformity & release profile
Multi-particulate coating problems
Wet & Hot-melt granulation & coating issues
Lack of effectiveness of the functional coating & homogeneity of the coating
Heat & moisture sensitive product
Tablet compressibility issues
Process capability improvements
Developing a new product from powder to the coated tablet
Replacing an existing material & process equipment
Scale-up/Scale-down of manufacturing process
Improving process yield/ energy consumption/ process time
Product development cost reduction
Support for the entire process from granulation to tableting and coating.
Manufacturing process development, optimisation & scale-up support from lab scale to commercial scale.
In-depth knowledge of standard and novel excipients used in pharmaceuticals and nutraceuticals.
Quality & Regulatory compliance assistance.
In-process testing & material characterisation support.
Comprehensive analysis of all required specifications for powder, granule and tablets.
Expert guidance for development of tableting for special products and geometries.
Design of Experiment (DoE) based approach to study the impact of process parameters and material variables on intermediate stages and final products.
Quality by Design (QbD) & Quality Risk Management (QRM) assistance.
Comprehensive expertise, simulation tools and test possibilities
Ventilus® Lab (Range: 0.4 – 4kg)
Ventilus®150 (Range: 7.5 – 75kg)
Granulation Line IGL 150 (Range: 20 – 60kg)
R&D tablet press KTP1X
Commercial scale tablet press K420 & S710
Tablet coater TPR 100 Optima (Range: 10 – 100kg)
Material Charcterisation instruments
Our expertise covers the whole processing process. We help with tableting expertise, but we also help you optimise the flow behavior or the compressibility of powders and granules. Furthermore, if required, we support you in choosing the right coating solution for final tablets.