Granulation refers to the process in which primary dust particles are made to adhere and form larger entities of multiple particles, called granules.
In wet granulation, the granules are formed by adding an agglutinative solution.
The granulation solution contains a solvent or carrier material that must be volatile so that it can be removed by drying. Typical fluids include water, ethanol and isopropanol which can also be used in combination. The liquid solution can be aqueous or solvent-based. Aqueous solutions have the advantage of being safer to handle than other solvents.
The granulation process combines one or more dust particles and forms a granule that will allow the formation of tablets within the required limits.

More and more it is important to optimise processes before industrialisation. Obviously to minimise time and cost risks.