Romaco at CIPM in Chongqing
New microdosing machine for sterile powders
Romaco Macofar MicroMaxX 24 microdosing machine
Romaco's new, intermittent motion Macofar MicroMaxX 24 microdosing machine will be launched in the market to coincide with the upcoming CIPM in Chongqing. With an output of up to 24,000 vials an hour, this technology represents the high performance class in aseptic powder filling and is mainly used to fill injectable powders. For this purpose, the MicroMaxX 24 is equipped with a dual powder dosing disc which allows multiple dosing into the same vial; alternatively, the product can be filled in two separate process steps. The vacuum/pressure system of the machine processes a wide range of pharmaceutical powders with different flow properties. Even very small product quantities right down to 20 mg can be dosed precisely. Furthermore, the MicroMaxX 24 has a filling station for sterile liquids.
Thanks to an innovative in-line weighing system, one hundred percent weight control is now possible even at full filling speed of 24,000 vials per hour. Measurements are carried out at two stations before and after filling the vials, which are subsequently closed in a sterile way with rubber stoppers. Romaco Macofar's MicroMaxX 24 can be configured with open RABS depending on the customer's requirements. The linear transport principle which was chosen for the vials and the slim design of the highly automated system together enable a reliable filling process. The use of servo technology simultaneously ensures a low-turbulence environment in the production area. In short, the MicroMaxX 24 from Romaco Macofar complies with even the strictest cGMP requirements for dosing sterile powders into vials.
Romaco Innojet VENTILUS® V 5 processing machine
The laboratory-scale version of the Romaco Innojet VENTILUS® V 5 is used for granulating, drying and coating particle sizes from 10 µm to 2 mm. Due to its special design and enhanced processing efficiency, the VENTILUS® V 5 allows up to 25% shorter batch times. The homogeneous flow conditions inside the cylindrical product container enable extremely gentle intermixing of the batch. The process air is controlled by the ORBITER booster, an ingenious container bottom consisting of overlapping circular plates. Together with the ROTOJET, the central bottom spray nozzle, the ORBITER booster forms an innovative functional unit that meets all the requirements for linear scale-ups. The air flow bed technology ensures accurate control of the product movement and equally precise application of the spray liquids. The resulting formulations can achieve the required release profile with between 10 and 15% less spray liquid.
On show at CIPM China in Chongqing from November 5 to 7, 2019 (International Expo Center, Stand S1-17).