Romaco at CIPM 2016 in Fuzhou, China

Well-positioned with processing solutions

Granulation, tableting, coating: at CIPM 2016 in Fuzhou the Romaco Group will show its solutions for tableting, granulating and coating pharmaceutical solids.

Romaco Kilian STYL’ONE Evolution: tableting robot for R&D applications

Romaco Kilian’s STYL’ONE Evolution tableting robot is predestined for a broad array of R&D applications and for producing very small batch sizes. With a maximum output of 1200 tablets per hour, this single-stroke press processes mono-layer, multilayer or core tablets (tab in tab). Equipped with a gravity or paddle force fill shoe, the STYL’ONE Evolution is capable of processing up to three different components and compressing tablets with as many as five layers. Any standard rotary press can be simulated thanks to ANALIS, the intelligent PAT software. The user simply selects the machine model and predefines the required tablet thickness or compression force. ANALIS then automatically determines the optimal compression parameters for the production scale. Since the necessary compression force profiles are created independently by the tableting robot, the time saving is enormous. The remarkable precision of the test batches means the powder properties can be analysed very realistically. Apart from developing new formulations, the STYL’ONE Evolution can thus also be utilised to optimise processes or troubleshoot errors. The highly efficient PAT system offers a continuous improvement in product quality.

Romaco Innojet VENTILUS® V 2.5: laboratory-scale processing machine

The laboratory-scale version of the Romaco Innojet VENTILUS® V 2.5 is used for granulating, drying and coating particle sizes from 10 µm to 2 mm. A proven all-rounder, it is the perfect system for handling powders, granulates, pellets and other free-flowing bulk materials for the pharmaceutical, food and chemical industries. Due to its special design and enhanced processing efficiency, the VENTILUS® V 2.5 allows up to 25% shorter batch times. The air flow bed technology ensures accurate control of the product movement and equally precise application of the spray liquids. The resulting formulations can achieve the required release profile with between 10 and 15% less spray liquid. The Romaco Innojet process technology is based on the internationally patented air flow bed technology originally developed by Dr. h.c. Herbert Hüttlin.

The VENTILUS® V 2.5 can be extended with a Romaco Innojet hot-melt unit for pharmaceutical applications. In a hot melt process, the API particles are coated with organic fats or waxes. Unlike aqueous or organic spray solutions, hot melt coatings do not have to be dried, because the cooling effect of the process air causes them to solidify. The processing times are substantially shorter as a result and productivity is accordingly higher. What’s more, since there is no need to heat the air for the hot melt process, energy efficiency is improved. Hot melt coatings are particularly suited for taste masks and/or as moisture barriers. Romaco Innojet has experience in supplying all essential equipment for this innovative coating process on any scale, from the V 2.5 lab size up to the V 1200 production version.

On show at CIPM China in Fuzhou from November 5 to 8, 2016 (International Hall, Booth 6-20).

Romaco Kilian STYL’ONE Evolution single-stroke press

Romaco Innojet VENTILUS® V 2.5 laboratory-scale processing machine