Am Heegwald 11 · 76227 Karlsruhe · Germany

28
Sep.
2017

Romaco at the AAPS Annual in San Diego (USA)

Focus on R&D

Romaco Kilian and Romaco Innojet to show technologies for pharmaceutical manufacturers’ laboratories.

Romaco Kilian STYL’ONE Evolution tableting robot

Pharmaceutical companies engaged in research have for years now trusted in Romaco Kilian’s STYL’ONE Evolution single-stroke press technology. This tableting robot has now been equipped with a whole set of new features for a broad array of R&D applications. The compression cycles have been speeded up by more than 60% and the maximum compression force increased to 50 kN in order to simulate high speed presses. Compression force profiles for all standard rotary presses can now be determined, for instance for the Romaco Kilian KTP 420X at up to 104 revolutions per minute. ANALIS, the intelligent PAT software, calculates all relevant tableting parameters based on compression force or displacement controlled cycles. The remarkable precision of the test batches – whether mono-layer, multilayer or core tablets – means powder properties can be analysed very realistically. This scalable tableting robot can thus also be utilised to optimise existing processes or troubleshoot errors. The STYL’ONE Evolution boasts a maximum output of 1,750 tablets an hour. Thanks to the ROCO Pack software, it is additionally possible to simulate the operation of granulating mills. The new models have a fully interchangeable process worktable, which is a great advantage if the products in question are highly abrasive. Cleaning and maintenance of the Romaco Kilian STYL’ONE Evolution are now much easier owing to the status lamps and utility connections integrated in the machine frame.

Romaco Innojet VENTILUS® V 2.5: laboratory-scale processing machine

The laboratory-scale version of the Romaco Innojet VENTILUS® V 2.5 is used for granulating, drying and coating particles of any size from 10 µm to 2 mm. Due to its enhanced processing efficiency and the special VENTILUS® design, up to 25% shorter batch times are achieved compared to conventional technologies. The homogeneous flow conditions in the cylindrical product container enable extremely gentle intermixing of the product. The process air is controlled by the ORBITER booster, an ingenious container bottom consisting of overlapping circular plates. Together with the ROTOJET, the central bottom spray nozzle, the ORBITER booster forms a unique functional unit that meets all the requirements for linear scale-ups. The innovative air flow bed technology ensures accurate control of the product movement and equally precise application of the spray liquids. The resulting formulations can achieve the required release profile with between 10 and 15% less spray liquid.

On show at the AAPS Annual in San Diego/USA from November 12 to 15, 2017 (Booth 2906).

Romaco Kilian STYL’ONE tableting robot

Romaco Innojet Ventilus V 2.5 laboratory-scale processing machine